The WebACT database
The results of the pre-computed blast comparisons between all pairs of sequences
are stored in a relational database along with the full EMBL format records for
each of the sequences.
In order for the blast results to be loaded into WebACT, the co-ordinates of
each blast hit need to be adjusted to take into account
the chunking of the query sequence, making each hit co-ordinate relative to
the full sequence record. Storing the data in
this manner allows for specific regions of the comparison
to be readily selected using a number of different methods.
The name of each gene is extracted from the full genome record, along with
the co-ordinates of that gene, and stored in the database. This allows the
region of a genome containing a particular gene to be quickly
identified, and a sequence record constructed representing the region
flanking the requested gene
Genome updates and new genomes
We have implemented an automatic update system within WebACT.
The genome sequences and annotations held at Genome Reviews are actively
curated and have a release cycle of 2 weeks. On a monthly basis, WebACT will
automatically check Genome Reviews data releases, and where necessary
will automatically update the local database for the genomes and comparison
This system will also check for any new genome sequences and will
automatically compare them to all the other genome sequences, and the stored
sequence, annotation and the comparison files will be added to the WebACT